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Methotrexate

UUID 1b527869-e5a6-4395-98f8-6b9b783d31a4
Flow Object IDfo-0e3b25bb59eefc9f
Source EF 3.1
Context Environmental → Air → Ground level → Rural (<1000 people/square mile)
CAS Numbers 59-05-2
EC Numbers 200-413-8
prefLabel
Language Value Provenance
en Methotrexate
altLabel ⓘ
Language Value Provenance
en 4-amino-10-methylfolic acid
en 4-amino-N(10)-methylpteroylglutamic acid
en Emtexate
en Ledertrexate
en MTX
en N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid
en N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
en Rheumatrex
en Trexall
en methotrexatum
en metotrexato
en (+)-Amethopterin
en (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid
en 4-Amino-<em>N</em><sup>10</sup>-methylfolic acid
en 4-Amino-<em>N</em><sup>10</sup>-methylpteroylglutamic acid
en <em>N</em>-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
en <em>N</em>-[<em>p</em>-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-(+)-glutamic acid
en <span class="text-smallcaps">L</span>-Amethopterin
en <span class="text-smallcaps">L</span>-Glutamic acid, <em>N</em>-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
en <span class="text-smallcaps">L</span>-Methotrexate
en Amethopterin
en Amethopterine
en Antifolan
en Beltrax
en CL 14377
en Caditrex
en Cytotrex
en Dermotrex
en EMT 25299
en Emthexate PF
en Emtrexate
en Folex
en Folex PFS
en Folitrax
en Glutamic acid, <em>N</em>-[<em>p</em>-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-
en Imutrex
en Jylamvo
en LMTX
en MeSH ID: D008727
en Merex
en Metatrexan
en Methocel
en Methocip
en Methotrexat-Ebewe
en Methotrexate LPF
en Methoxtrexate
en Methylaminopterin
en Metorex
en Metrex
en Mexate
en Mexate-AQ
en NSC 740
en Nordimet
en Oncotrex
en Otrexup
en R 9985
en Rasuvo
en Remtrex
en Trilem
en Zexate
References
Shared Properties
Predicate Value
Formal charge 0
InChIKey FBOZXECLQNJBKD-ZDUSSCGKSA-N
InChI InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
IUPAC name (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]glutaric acid, (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid, (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid, (2S)-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, (2S)-2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid
Molecular formula C20H22N8O5
Molecular mass 454.447
Monoisotopic mass 454.17132
SMILES CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O, CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O, CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

Source List References

List Version Source Flow UUID Source Flow Name
EF 3.1 1b527869-e5a6-4395-98f8-6b9b783d31a4 methotrexate

Concept Associations

Source List Source Flow Source Context Unit Match Type Conversion Provenance
EF 3.1 methotrexate Emissions/Emissions to air/Emissions to air, unspecified (long-term) kg exactMatch —

Consolidated Field Provenance

0 total PROV activity record(s) for this flow.

Field Change Count Latest Time Transformers Latest Comment
altLabel 1 — consensus_match group_key=methotrexate||dimension=Environmental > media=Air > strata=Ground level > population_density=Rural (<1000 people/square mile); cas=59-05-2; added Common Chemistry CAS names as altLabel: (+)-Amethopterin, (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid, 4-Amino-<em>N</em><sup>10</sup>-methylfolic acid, 4-Amino-<em>N</em><sup>10</sup>-methylpteroylglutamic acid, <em>N</em>-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, <em>N</em>-[<em>p</em>-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-(+)-glutamic acid, <span class="text-smallcaps">L</span>-Amethopterin, <span class="text-smallcaps">L</span>-Glutamic acid, <em>N</em>-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-Methotrexate, Amethopterin, Amethopterine, Antifolan, Beltrax, CL 14377, Caditrex, Cytotrex, Dermotrex, EMT 25299, Emthexate PF, Emtrexate, Folex, Folex PFS, Folitrax, Glutamic acid, <em>N</em>-[<em>p</em>-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-, Imutrex, Jylamvo, LMTX, MeSH ID: D008727, Merex, Metatrexan, Methocel, Methocip, Methotrexat-Ebewe, Methotrexate LPF, Methoxtrexate, Methylaminopterin, Metorex, Metrex, Mexate, Mexate-AQ, NSC 740, Nordimet, Oncotrex, Otrexup, R 9985, Rasuvo, Remtrex, Trilem, Zexate; object_uuid=fo-0e3b25bb59eefc9f
cas_match_labels 1 — consensus_match group_key=methotrexate||dimension=Environmental > media=Air > strata=Ground level > population_density=Rural (<1000 people/square mile); group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'59-05-2': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-0e3b25bb59eefc9f: {'59-05-2': 'exactMatch'}

Context Attributes

AttributeValue
dimensionEnvironmental
mediaAir
strataGround level
population_densityRural (<1000 people/square mile)

Consensus Changes

Field Old Value New Value Comment
altLabel [{'@value': '4-amino-10-methylfolic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:4-amino-10-methylfolic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': '4-amino-N(10)-methylpteroylglutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:4-amino-N(10)-methylpteroylglutamic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Emtexate', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Emtexate', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Ledertrexate', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Ledertrexate', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'MTX', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:MTX', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Rheumatrex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Rheumatrex', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Trexall', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Trexall', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'methotrexatum', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:methotrexatum', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'metotrexato', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:metotrexato', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}] [{'@value': '4-amino-10-methylfolic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:4-amino-10-methylfolic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': '4-amino-N(10)-methylpteroylglutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:4-amino-N(10)-methylpteroylglutamic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Emtexate', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Emtexate', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Ledertrexate', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Ledertrexate', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'MTX', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:MTX', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Rheumatrex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Rheumatrex', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'Trexall', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:Trexall', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'methotrexatum', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:methotrexatum', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': 'metotrexato', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'chebi_altlabels', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['label:metotrexato', 'http://purl.obolibrary.org/obo/CHEBI_44185', 'EF 3.1'], 'prov:wasDerivedFrom': 'chebi synonym match'}}, {'@value': '(+)-Amethopterin', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '(2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '4-Amino-<em>N</em><sup>10</sup>-methylfolic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '4-Amino-<em>N</em><sup>10</sup>-methylpteroylglutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '<em>N</em>-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '<em>N</em>-[<em>p</em>-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-(+)-glutamic acid', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '<span class="text-smallcaps">L</span>-Amethopterin', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '<span class="text-smallcaps">L</span>-Glutamic acid, <em>N</em>-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': '<span class="text-smallcaps">L</span>-Methotrexate', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Amethopterin', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Amethopterine', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Antifolan', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Beltrax', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'CL 14377', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Caditrex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Cytotrex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Dermotrex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'EMT 25299', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Emthexate PF', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Emtrexate', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Folex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Folex PFS', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Folitrax', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Glutamic acid, <em>N</em>-[<em>p</em>-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Imutrex', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'Jylamvo', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 'https://commonchemistry.cas.org/detail?cas_rn=59-05-2'], 'prov:wasDerivedFrom': 'common chemistry CAS lookup'}}, {'@value': 'LMTX', '@language': 'en', 'source': {'prov:wasGeneratedBy': 'consensus_match', 'prov:wasAttributedTo': 'consensus-flow-list', 'prov:hadPrimarySource': ['CAS:59-05-2', 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(2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid, 4-Amino-<em>N</em><sup>10</sup>-methylfolic acid, 4-Amino-<em>N</em><sup>10</sup>-methylpteroylglutamic acid, <em>N</em>-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, <em>N</em>-[<em>p</em>-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-(+)-glutamic acid, <span class="text-smallcaps">L</span>-Amethopterin, <span class="text-smallcaps">L</span>-Glutamic acid, <em>N</em>-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-Methotrexate, Amethopterin, Amethopterine, Antifolan, Beltrax, CL 14377, Caditrex, Cytotrex, Dermotrex, EMT 25299, Emthexate PF, Emtrexate, Folex, Folex PFS, Folitrax, Glutamic acid, <em>N</em>-[<em>p</em>-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-, Imutrex, Jylamvo, LMTX, MeSH ID: D008727, Merex, Metatrexan, Methocel, Methocip, Methotrexat-Ebewe, Methotrexate LPF, Methoxtrexate, Methylaminopterin, Metorex, Metrex, Mexate, Mexate-AQ, NSC 740, Nordimet, Oncotrex, Otrexup, R 9985, Rasuvo, Remtrex, Trilem, Zexate; object_uuid=fo-0e3b25bb59eefc9f
cas_match_labels None {'59-05-2': 'exactMatch'} group_key=methotrexate||dimension=Environmental > media=Air > strata=Ground level > population_density=Rural (<1000 people/square mile); group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'59-05-2': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-0e3b25bb59eefc9f: {'59-05-2': 'exactMatch'}

PROV-O Consensus Activity Trail

No PROV-O consensus activities found for this flow.

Full Flow JSON

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