Trimethoprim
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-078c320fd2607008
Changes
57| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 19,080 | bootstrap_labels | prefLabel | — | [{"@value":"trimethoprim","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"c… | Bootstrapped prefLabel from legacy name field |
| 19,081 | bootstrap_labels | name | trimethoprim | — | Purged legacy name field to enforce prefLabel usage |
| 19,082 | bootstrap_labels | synonyms | ["trimethoprim","2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidin","2,4-pyrimidinediamine,5-[3,4,5-trimethoxyphenyl)met… | [] | Removed legacy synonyms field in favor of structured labels |
| 19,301 | bootstrap_labels | synonyms | ["2,4-Diamino-5-(3',4',5'-trimethoxybenzyl)pyrimidine","2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine","2,4-Diamino-… | [] | Removed legacy synonyms field in favor of structured labels |
| 61,533 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 61,534 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 62,313 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 62,314 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 70,117 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 70,118 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 112,619 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 112,620 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 117,005 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 117,006 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 118,181 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 118,182 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 132,595 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 132,596 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 152,687 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 152,688 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 176,689 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 176,690 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 176,823 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 176,824 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 179,551 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 179,552 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 180,003 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 180,004 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 201,737 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 201,738 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 219,562 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 225,439 | normalize_name_case | prefLabel | [{"@value":"trimethoprim","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"c… | [{"@value":"Trimethoprim","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"c… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 244,946 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C14H18N4O3… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 244,947 | enrich_references | skos_definition | — | [{"@value":"An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzen… | Merged ChEBI/PubChem definitions into skos:definition |
| 244,948 | enrich_references | references | [] | [{"@id":"beilstein:625127","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['738-70-5']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_45924']; candidate_pubchem_cids=[5578, 21109, 3084396]; selected_pubchem_cids=[5578]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 256,877 | chebi_altlabels | altLabel | [] | [{"@value":"2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | Added 5 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 272,981 | consensus_match | altLabel | [{"@value":"2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | [{"@value":"2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | group_key=trimethoprim||dimension=Environmental > media=Air > indoor=Unknown; cas=738-70-5; added Common Chemistry CAS names as altLabel: 2,4-Diamino-5-(3′,4′,5′-trimethoxybenzyl)pyrimidine, 2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-, BW 56-72, Infectotrimet, Instalac, MeSH ID: D014295, Monotrim, NIH 204, NSC 106568, Pyrimidine, 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-, Syraprim, Tiempe, Trimanyl, Trimethioprim, Trimetoprim, Trimogal, Trimopan, Triprim, Uretrim, Wellcoprim; object_uuid=fo-078c320fd2607008 |
| 272,982 | consensus_match | cas_match_labels | — | {"738-70-5":"exactMatch"} | group_key=trimethoprim||dimension=Environmental > media=Air > indoor=Unknown; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'738-70-5': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-078c320fd2607008: {'738-70-5': 'exactMatch'} |
| 278,653 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C14H18N4O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C14H18N4O3… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine' |
| 285,432 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C14H18N4O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C14H18N4O3… | rdkit_post_consensus from 'COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 291,103 | strip_catalogue_altlabels | altLabel | [{"@value":"2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | [{"@value":"2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | Removed 2 catalogue altLabel value(s): 'NIH 204' (grade code), 'NSC 106568' (registry code) |
| 311,824 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/25bb6803-30a5-… | associations resolved on the elementary layer |
| 312,213 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/2714c004-705f-… | associations resolved on the elementary layer |
| 316,114 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/32afa232-99a1-… | associations resolved on the elementary layer |
| 337,344 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/696e3d88-e49b-… | associations resolved on the elementary layer |
| 339,536 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/70ea9e82-1976-… | associations resolved on the elementary layer |
| 340,123 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/72ecf0e1-94a2-… | associations resolved on the elementary layer |
| 347,327 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/8b38adcd-7be9-… | associations resolved on the elementary layer |
| 357,397 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/acde2326-45ab-… | associations resolved on the elementary layer |
| 369,397 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/d64908c2-c82d-… | associations resolved on the elementary layer |