Hydroxyurea
fo-093a852c892b7c7c
Identity
- Type
- Neutral molecule
- CAS
- 127-07-1
- EC
- 204-821-7
- Origin
- EF 3.1 hybrid_name_cas_v1
- Changes
- 59 across every transformer
Structure
Alternative labels
36- 1-Hydroxyurea
- Biosupressin
- carbamohydroxamic acid
- carbamohydroximic acid
- carbamoyl oxime
- carbamyl hydroxamate
- Cytodrox
- Droxia
- Hidrix
- hidroxicarbamida
- HU
- hydrea
- Hydreia
- Hydroxycarbamid
- Hydroxycarbamide
- hydroxycarbamidum
- Hydroxycarbamine
- Hydroxyharnstoff
- Hydroxylamine, N-(aminocarbonyl)-
- Hydroxylurea
- Hydura
- Hydurea
- Litaler
- Litalir
- MeSH ID: D006918
- Mylocel
- N-carbamoylhydroxylamine
- N-HYDROXYUREA
- NCI C04831
- Onco-Carbide
- Oxyrea
- oxyurea
- Siklos
- Urea, hydroxy-
- Urea, N-hydroxy-
- Xromi
Properties
| Property | Value |
|---|---|
| Elemental charge chemrof:elemental_charge | 0 |
| InChI2D key string chemrof:inchi2d_key_string | VSNHCAURESNICA-UHFFFAOYSA-N |
| InChI2D string chemrof:inchi2d_string | InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4) |
| IUPAC name chemrof:IUPAC_name | Hydroxyurea |
| Molecular formula chemrof:molecular_formula | CH4N2O2 |
| Molecular mass chemrof:molecular_mass | 76.055 |
| Monoisotopic mass chemrof:monoisotopic_mass | 76.027277, 76.02728 |
| SMILES string chemrof:smiles_string | NC(=O)NO |
Known URLs
52Where else this substance is described. Collected while the pipeline resolved it — from ChEBI's cross-references, from PubChem's identifier list, and from the CAS number — so a link here is a record the merge actually read, not a search it suggests.
| Resource | URL | Recorded by |
|---|---|---|
| beilstein | beilstein:1741548 | enrich_references.chebi_xrefs |
| CAS Common Chemistry | https://commonchemistry.cas.org/detail?cas_rn=127-07-1 | enrich_references.chebi_xrefs |
| ChEBI | https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:44423 | enrich_references.chebi_id_link |
| chem.echa.europa.eu | https://chem.echa.europa.eu/100.004.384 | enrich_references.pubchem_identifier_url |
| comptox.epa.gov | https://comptox.epa.gov/dashboard/DTXSID6025438 | enrich_references.pubchem_identifier_url |
| DrugBank | https://go.drugbank.com/drugs/DB01005 | enrich_references.chebi_xrefs |
| drugbank.ca | https://www.drugbank.ca/drugs/DB01005 | enrich_references.pubchem_identifier_url |
| drugcentral | drugcentral:1399 | enrich_references.chebi_xrefs |
| drugcentral.org | https://drugcentral.org/drugcard/1399 | enrich_references.pubchem_identifier_url |
| dtp.cancer.gov | https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=32065 | enrich_references.pubchem_identifier_url |
| dtp.cancer.gov | https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=757072 | enrich_references.pubchem_identifier_url |
| ebi.ac.uk | https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL467 | enrich_references.pubchem_identifier_url |
| gmelin | gmelin:130423 | enrich_references.chebi_xrefs |
| gsrs.ncats.nih.gov | https://gsrs.ncats.nih.gov/ginas/app/beta/substances/X6Q56QN5QC | enrich_references.pubchem_identifier_url |
| HMDB | https://hmdb.ca/metabolites/HMDB0015140 | enrich_references.chebi_xrefs |
| jglobal.jst.go.jp | http://jglobal.jst.go.jp/en/redirect?Nikkaji_No=J2.937H | enrich_references.pubchem_identifier_url |
| KEGG | https://www.genome.jp/entry/C07044 | enrich_references.chebi_xrefs |
| KEGG | https://www.genome.jp/entry/D00341 | enrich_references.chebi_xrefs |
| kegg.jp | https://www.kegg.jp/entry/C07044 | enrich_references.pubchem_identifier_url |
| kegg.jp | https://www.kegg.jp/entry/D00341 | enrich_references.pubchem_identifier_url |
| metabolomicsworkbench.org | https://www.metabolomicsworkbench.org/data/StructureData.php?RegNo=43251 | enrich_references.pubchem_identifier_url |
| MetaCyc | https://metacyc.org/compound?orgid=META&id=HYDROXY-UREA | enrich_references.chebi_xrefs |
| ncithesaurus.nci.nih.gov | https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C560 | enrich_references.pubchem_identifier_url |
| patent | patent:US2705727 | enrich_references.chebi_xrefs |
| pdb-ccd | pdb-ccd:NHY | enrich_references.chebi_xrefs |
| pharmgkb.org | https://www.pharmgkb.org/chemical/PA449942 | enrich_references.pubchem_identifier_url |
| pharos.nih.gov | https://pharos.nih.gov/ligands/YS9WPYDSAP5A | enrich_references.pubchem_identifier_url |
| platform.opentargets.org | https://platform.opentargets.org/drug/CHEMBL467 | enrich_references.pubchem_identifier_url |
| PubChem | https://pubchem.ncbi.nlm.nih.gov/compound/3657 | enrich_references.pubchem_compound |
| PubChem | https://pubchem.ncbi.nlm.nih.gov/erg/#2811 | enrich_references.pubchem_identifier_url |
| PubChem | https://pubchem.ncbi.nlm.nih.gov/substance/?source=niaid&sourceid=006310 | enrich_references.pubchem_identifier_url |
| PubChem | https://pubchem.ncbi.nlm.nih.gov/substance/?source=niaid&sourceid=566397 | enrich_references.pubchem_identifier_url |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/11285159 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/11298103 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/11364534 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/11365149 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/11391710 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/12107454 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/14988684 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/15772364 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/15994344 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/16356682 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/22983419 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/23318979 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/23643402 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/23696560 | enrich_references.chebi_xrefs |
| PubMed | https://pubmed.ncbi.nlm.nih.gov/9271088 | enrich_references.chebi_xrefs |
| reaxys | reaxys:1741548 | enrich_references.chebi_xrefs |
| rxnav.nlm.nih.gov | https://rxnav.nlm.nih.gov/id/rxnorm/5552 | enrich_references.pubchem_identifier_url |
| Wikidata | https://www.wikidata.org/wiki/Q212272 | enrich_references.pubchem_identifier_url |
| Wikipedia | https://en.wikipedia.org/wiki/Hydroxycarbamide | enrich_references.pubchem_identifier_url |
| Wikipedia | https://en.wikipedia.org/wiki/Hydroxyurea | enrich_references.chebi_xrefs |
Elementary flows
13| Flow | Context | Source | Unit | CFs |
|---|---|---|---|---|
| c5c1b5d8-d38a-42f1-89b3-d34c7963f2b0 | Environmental → Air → Aircraft cruise height | EF 3.1 | kg | 2 |
| 3b1e8653-9cfb-423d-bcff-34d19162f875 | Environmental → Air → Ground level → Urban (>1000 people/square mile) | EF 3.1 | kg | 2 |
| 18126c1d-eceb-45b7-8df8-7aeb90abd27b | Environmental → Air → Indoor | EF 3.1 | kg | 2 |
| 2049a719-d042-44dd-9121-f0dcb67448ed | Environmental → Air → Long-term | EF 3.1 | kg | 0 |
| 3bf96958-d70b-4fc9-9ed7-f7d2e5e43782 | Environmental → Air → Medium stack, <150 meters → Rural (<1000 people/square mile) | EF 3.1 | kg | 2 |
| 6f488e5c-ffd4-4af0-81db-6a9922b57892 | Environmental → Air → Unknown | EF 3.1 | kg | 2 |
| aadab4f5-b6e7-4178-80c1-752ca2d5650c | Environmental → Ground → Agricultural | EF 3.1 | kg | 2 |
| c107661c-efe7-4f88-b2fa-878eaf3fda9c | Environmental → Ground → Non-agricultural | EF 3.1 | kg | 2 |
| 72fd8c27-2185-49a4-90de-297e8bd4b953 | Environmental → Ground → Unknown | EF 3.1 | kg | 2 |
| 631d4617-11f5-4121-9345-3d30f64e0290 | Environmental → Water → Long-term | EF 3.1 | kg | 0 |
| 572fa7fb-8f10-4eb6-af8a-963f6df00ca6 | Environmental → Water → Ocean | EF 3.1 | kg | 2 |
| 443dd883-3264-4070-8042-56c944d15e4c | Environmental → Water → Surface water | EF 3.1 | kg | 2 |
| 6a8bb83b-b7b1-4257-a227-316cebe23d17 | Environmental → Water → Unknown | EF 3.1 | kg | 2 |
History
Everything that changed this substance (59 changes)
Full record
Flow object JSON
{
"flow_object_id": "fo-093a852c892b7c7c",
"prefLabel": [
{
"@value": "Hydroxyurea",
"@language": "en",
"@lang": "en",
"provenance": {
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],
"prov:wasDerivedFrom": "Common Chemistry / ChEBI primary name agreement"
}
}
],
"altLabel": [
{
"@value": "1-Hydroxyurea",
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],
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},
{
"@value": "Biosupressin",
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},
{
"@value": "carbamohydroxamic acid",
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},
{
"@value": "carbamohydroximic acid",
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}
},
{
"@value": "carbamoyl oxime",
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}
},
{
"@value": "carbamyl hydroxamate",
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}
},
{
"@value": "Cytodrox",
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],
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},
{
"@value": "Droxia",
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],
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},
{
"@value": "Hidrix",
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],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "hidroxicarbamida",
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}
},
{
"@value": "HU",
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],
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}
},
{
"@value": "hydrea",
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}
},
{
"@value": "Hydreia",
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],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Hydroxycarbamid",
"@language": "en",
"@lang": "en",
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],
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}
},
{
"@value": "Hydroxycarbamide",
"@language": "en",
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}
},
{
"@value": "hydroxycarbamidum",
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],
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}
},
{
"@value": "Hydroxycarbamine",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
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"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Hydroxyharnstoff",
"@language": "en",
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"provenance": {
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],
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}
},
{
"@value": "Hydroxylamine, N-(aminocarbonyl)-",
"@language": "en",
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"provenance": {
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],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Hydroxylurea",
"@language": "en",
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"prov:hadPrimarySource": [
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"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Hydura",
"@language": "en",
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],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Hydurea",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
"CAS:127-07-1",
"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Litaler",
"@language": "en",
"@lang": "en",
"provenance": {
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"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Litalir",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
"CAS:127-07-1",
"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "MeSH ID: D006918",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
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"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Mylocel",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
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],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "N-carbamoylhydroxylamine",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "chebi_altlabels",
"prov:wasAttributedTo": "consensus-flow-list",
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"http://purl.obolibrary.org/obo/CHEBI_44423"
],
"prov:wasDerivedFrom": "chebi synonym match"
}
},
{
"@value": "N-HYDROXYUREA",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "chebi_altlabels",
"prov:wasAttributedTo": "consensus-flow-list",
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"EF 3.1",
"http://purl.obolibrary.org/obo/CHEBI_44423"
],
"prov:wasDerivedFrom": "chebi synonym match"
}
},
{
"@value": "NCI C04831",
"@language": "en",
"@lang": "en",
"provenance": {
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"prov:hadPrimarySource": [
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],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Onco-Carbide",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
"CAS:127-07-1",
"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "Oxyrea",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "consensus_match",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
"CAS:127-07-1",
"EF 3.1",
"https://commonchemistry.cas.org/detail?cas_rn=127-07-1"
],
"prov:wasDerivedFrom": "common chemistry CAS lookup"
}
},
{
"@value": "oxyurea",
"@language": "en",
"@lang": "en",
"provenance": {
"prov:wasGeneratedBy": "chebi_altlabels",
"prov:wasAttributedTo": "consensus-flow-list",
"prov:hadPrimarySource": [
"EF 3.1",
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Something wrong here?
- This substance is published under the wrong name
- This is not that chemical
- This record is two substances, or it is a second copy of one
You do not need to run a build or clone anything. Name the record and say what your evidence is; the measurement is done for you. How contributing works